Inhibition of Cytokine Release From Alveolar Macrophages in Pulmonary Sarcoidosis by Pentoxifylline*Comparison With Dexamethasone®金宝搏网站登录技巧 -网聚医学的力量

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Inhibition of Cytokine Release From Alveolar Macrophages in Pulmonary Sarcoidosis by Pentoxifylline*Comparison With Dexamethasone

作者：Zhaohui Tong, MD; Huaping Dai, MD; Baomin Chen; Ziad Abdoh, MD; Josune Guzman, MD; and Ulrich Costabel, MD, FCCP 来源：金宝搏网站登录技巧日期：2017-12-11

导读

Study objectives: Pentoxifylline (POF) has been shown to suppress the cytokine production from lipopolysaccharide (LPS)-stimulated monocytes/alveolar macrophages (AMs). Sarcoidosis is a granulomatous disease that is driven by the action of tumor necrosis

Study objectives: pentoxifylline (POF) has been shown to suppress the cytokine production from lipopolysaccharide (LPS)-stimulated monocytes/alveolar macrophages (AMs). sarcoidosis is a granulomatous disease that is driven by the action of tumor necrosis factor (TNF)- and other proinflammatory cytokines. In this study, we aimed to investigate the effects of POF on the production of TNF-, interleukin (IL)-1, IL-6, IL-8, IL-10, and the soluble TNF receptors (sTNFRs) 1 and 2 from AMs in sarcoidosis, and we also compared them with those of dexamethasone (DEX).