奥硝唑注射液致固定性药疹1例
近期，清华大学第一附属医院北京华信医院药学部研究人员发表《奥硝唑注射液致固定性药疹1例》研究，该文章发表于2015年1期的《中国药物应用与监测》上。
近期，清华大学第一附属医院北京华信医院药学部研究人员发表《奥硝唑注射液致固定性药疹1例》研究，该文章发表于2015年1期的《中国药物应用与监测》上。
1例80岁女性患者1年前行胆囊切除术，近日因胆道感染、反流性食管炎、冠状动脉粥样硬化性心脏病等入院治疗。给予奥硝唑注射液(0.5 g，bid，ivgtt)和头孢曲松(2 g，qd，ivgtt)进行抗感染，奥美拉唑钠(40 mg，bid，ivgtt)抑制胃酸治疗。用药第4天，患者双足出现多个水疱样固定性药疹。立即停用奥硝唑注射液，口服氯雷他定片(10 mg，qd)，同时外用卤米松膏，抽疱湿敷治疗7 d后，患者双足固定性药疹结痂好转。
英文摘要：
One case of fixed drug eruption caused by ornidazole injection
Abstract： One 80-year-old female patient was hospitalized for biliary tract infection, reflux esophagitis, coronary atherosclerosis heart disease after cholecystectomy surgery 1 year ago. Ornidazole injection (0.5 g, bid, ivgtt) and ceftriaxone (2 g, qd, ivgtt) were used for anti-infection, omeprazole sodium (40 mg, bid, ivgtt) was utilized for gastric acid inhibition. On the fourth day, a few vesicular fixed drug eruptions occurred on the patient's feet. Ornidazole injection was stopped immediately, loratadine (10 mg, qd) and halometasone ointment were given. Suction blisters and wet for 7 days, the fixed drug eruption on the patient's feet began to escharosis and improved.
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