Pediatric Critical Care Medicine:

May 2014 - Volume 15 - Issue 4_suppl - p 39

doi: 10.1097/01.pcc.0000448877.33761.b1

THE RELATIONSHIP BETWEEN NUTRITIONAL ADEQUACY AND CLINICAL OUTCOMES IN CHILDREN WITH SEPSIS OR SEVERE SEPSIS

Fang, B.; Qian, S.

ABSTRACT

Background and aims: Sepsis/severe sepsis is a common disease in PICU and also the most common cause of death in critically ill children. The nutritional adequacy is closely related to clinical prognosis.

Aims: To examine the adequacy of energy and protein intake in these children; to describe their relationship to clinical outcomes and disease condition.

Methods: We conducted a prospective, observational study at PICU of Beijing Children’s Hospital from November 2012 to April 2013 for children with sepsis/severe sepsis. Recorded actual intakes of energy/protein, calculated the adequacy of energy/protein intakes. IRB approval had been gotten.

Results: Total 62 children were enrolled with median age 13 months.62 children’s energy adequacy via EN or total energy adequacy separately were 0.84 ± 0.38 and 0.92 ± 0.30; while adequacy for protein were 0.94 ± 0.4 and 0.99 ± 0.40.27 children’s total energy intakes reached energy goal, while 30 for protein. The average adequacy of energy and protein intakes could reach 80% at the second PICU day, and nearly 80% children’s energy and protein adequacy could reach 70% in PICU. Children with inadequate energy intake had significantly older age (P=0.02), higher weight (P=0.01), higher rate of endotracheal intubation (EI) (P=0.01), longer days of EI(P=0.03), higher ratio of EI days/PICU days (P=0.02) and higher hospitalization expenses (P=0.04), but lower PCI score (P=0.02).children with inadequate total protein intake had higher weight (P=0.01) and larger number of organ dysfunction (p=0.03).

Conclusions: Children in this study have relatively higher energy/protein adequacy. Children with inadequate nutrition may suffer poor clinical outcome.