首都医科大学附属北京天坛医院王一龙、赵性泉和王拥军等学者探索了中国成人短暂性脑缺血发作(TIA)的患病率、公众认识和治疗情况，结果表明，我国TIA普遍流行，估计患病人群约2390万；公众对TIA认识非常有限；TIA似乎是我国漏诊和未治疗的主要疾病，迫切需要采取措施去改善TIA管理。相关论文5月8日在线发表于《神经病学》(Neurology)杂志。

        该复杂、多级、概率抽样设计的横断面研究在全国范围内纳入了98658例成人受试者。以面对面交流时受试者回想起症状或自我记录的TIA病史初次鉴别可能的TIA病例，再通过电话或谈话记录由神经病学专家制定最终的诊断。

        结果显示，年龄标化的TIA患病率为2.27%。在临床中，仅有16.0%的受试者在研究前被确诊。

        TIA在以下人群中患病率更高，这些人群分别为女性、高龄、受教育较少、当前吸烟者、居住在农村或欠发达地区，以及有吸烟史、高血压、心肌梗死、血脂异常或188bet在线平台网址 病史人群。

        基于调查的反馈，约3.08%的成人具备TIA知识。在TIA患者中，仅5.02%的人群接受了治疗，接受指南推荐治疗人群为4.07%。

        参考文献：Yilong Wang,et al. 1. Published online before print May 8, 2015, doi: 10.1212/WNL.0000000000001665Neurology 10.1212/WNL.0000000000001665

Prevalence, knowledge, and treatment of transient ischemic attacks in China
1. Yilong Wang, MD, PhD,
2. Xingquan Zhao, MD, PhD,
3. Yong Jiang, PhD,
4. Hao Li, PhD,
5. Limin Wang, MD,
6. S. Claiborne Johnston, MD, PhD,
7. Liping Liu, MD, PhD,
8. Ka Sing Lawrence Wong, FRCP,
9. Chunxue Wang, MD, PhD,
10. Yuesong Pan, MD,
11. Jing Jing, MD, PhD,
12. Jie Xu, MD, PhD,
13. Xia Meng, MD, PhD,
14. Mei Zhang, MD,
15. Yichong Li, PhD,
16. Yong Zhou, PhD,
17. Wenhua Zhao, PhD and
18. Yongjun Wang, MD
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1. Correspondence to Dr. Yongjun Wang: yongjunwang1962@gmail.com or Dr. Yilong Wang: yilong528@gmail.com
1. Published online before print May 8, 2015, doi: 10.1212/WNL.0000000000001665Neurology 10.1212/WNL.0000000000001665
ABSTRACT
Objectives: To investigate the prevalence, knowledge, and treatment of TIA in a Chinese adult population.
Methods: We conducted a complex, multistage, probability sampling–designed, cross-sectional, nationwide survey of 98,658 Chinese adults in 2010. Possible TIA cases were first identified by symptoms recall or self-reported history of TIA through face-to-face interviews, and the final diagnosis was then made by expert neurologists through phone interviews or record review.
Results: The age-standardized prevalence of TIA was 2.27%. Clinically, only 16.0% of the participants were diagnosed before the study. The prevalence of TIA was higher in women and in patients who were older, had less education, were current smokers, lived in rural or undeveloped areas, and had a history of stroke, hypertension, myocardial infarction, dyslipidemia, or diabetes. Based on the survey responses, approximately 3.08% of Chinese adults had knowledge of TIA. Among patients with TIA, only 5.02% received treatment and 4.07% received guideline-recommended therapy.
Conclusions: TIA is prevalent and an estimated 23.9 million people in China may have experienced a TIA. Public knowledge on TIA is very limited. TIA appears to be largely undiagnosed and untreated in China. There is an urgent need to develop strategies to improve the identification and appropriate management of TIA.