肾内科

盆腔器官脱垂女性患者器官功能及术后发病率分析

作者:Joy A. Greer, Gina M. Northington, Heidi S. Harvie, Saya Segal, et al. 来源:Journal of Urology 日期:2013-03-12
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Functional Status and Post-Operative Morbidity in Older Women With Prolapse
 
 
Abstract 
Purpose
To determine the relationship of preoperative functional status with post-operative morbidity following pelvic organ prolapse (POP) surgery in women older than 60 years.
 
Materials and Methods
Retrospective cohort study of 223 women older than 60 years who underwent surgery for Stage II or greater POP. Our exposure was pre-operative functional status, defined as American Society of Anesthesia (ASA) physical status class. We compared post-operative outcomes (length of stay in a medical facility and number and severity of post-operative complications) in women with low functional status (ASA class III) to women with high functional status (ASA class I & II). We determined the association of preoperative functional status with post-operative outcomes using multivariable analysis.
 
Results
Women in ASA class III were significantly likely to be older (72.7±7.3 vs 68.3±6.5 years), of non-white ethnicity (36.1% vs 20.1%), have higher BMI (29.5±5.6 vs 26.1±3.8) and worse functional co-morbidity score (median 3 vs. 2), and have undergone obliterative surgery (33.3% vs 9.1%) than women in ASA classes I & II, (all p<0.05). Low preoperative functional status was independently associated with increased length of stay in a medical facility (2.13 days, 95%CI 0.57, 3.70, p<0.01) and post-operative complications (OR 2.17, 95% CI 1.03, 4.56), after adjusting for age, BMI, non-white ethnicity, number of co-morbidities, surgeon, and type of surgery.
 
Conclusions
Preoperative functional status defined by ASA class is significantly associated with post-operative length of stay and complications. Preoperative functional status is useful for predicting post-operative outcomes in older women undergoing POP surgery.
 
 
 
 
http://www.jurology.com/article/S0022-5347(13)03525-8/abstract
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