2型188bet在线平台网址 患者CKD发病率：西班牙PERCEDIME2研究
作者：Antonio Rodriguez-Poncelas, Josep Garre-Olmo, Gabriel Coll-de Tuero et al. 来源：BMC Nephrology 日期：2013-02-25
导读
Prevalence of chronic kidney disease in patients with type 2 diabetes in Spain: PERCEDIME2 study
Bakground
The objective of this study was to determinate the prevalence of chronic kidney disease (CKD) and the different stages of CKD in patients with type 2 diabetes mellitus (DM2) treated in primary care consults in Spain.
Methods
A national cross-sectional study was performed in primary care consults. The following data were collected: demographic and anthropometric information; list of present cardiovascular risk factors (CVRF); previous macrovascular and microvascular disease history; physical examination and analytical data from the previous 12 months, including the urine albumin-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) to evaluate renal function.
Results
With regard to the patients, 27.9% presented some degree of CKD as follows: 3.5% with stage 1; 6.4% with stage 2; 16.8% with stage 3 (11.6% with stage 3A and 5.2% with stage 3B); and 1.2% with stages 4 and 5. The prevalence of patients with UACR >= 30 mg/g was 15.4% (13% microalbuminuria and 2.4% macroalbuminuria). Renal impairment (RI) was found in 206 patients (18%) of whom 133 patients (64.6%) was stage 3A, 60 patients (29.1%) was stage 3B and 13 patients (6.3%) stages 4 and 5. Among patients with RI, 143 patients (69.4%) had normoalbuminuria.
The following variables were significantly associated with CKD: age; sex (women); systolic arterial blood pressure (SABP) >= 150 mmHg; and a previous history of cardiovascular disease.
Conclusions
The results showed that the prevalence for any type of CKD was 27.9%. A systematic determination of UACR and eGFR may contribute to an early diagnosis, thus allowing intervention during the initial stages of the disease when treatment is more efficient.
http://www.biomedcentral.com/1471-2369/14/46/abstract
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