隐睾与精索静脉曲张年轻患者精液分析结果对比
作者：Matthew S. Christman, Stephen A. Zderic, Thomas F. Kolon 来源：Journal of Urology 日期：2013-02-19
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Comparison of Semen Analyses amongst Youths with a History of Cryptorchidism or Varicocele
Abstract
Purpose
We aimed to determine the relative semen quality of youths with a diagnosis of cryptorchidism (UDT) or varicocele (Vx), as a surrogate for ultimate paternity potential. We hypothesized that youths with a Vx would have a lower risk of subfertility, based on semen analysis (SA), than their counterparts with surgically corrected UDT.
Materials and Methods
A retrospective review of patients with a history of UDT or Vx was performed. Patients were placed into one of three groups based on their diagnosis: Group1, untreated Vx; Group2, treated bilateral UDT; Group3, treated unilateral UDT. Age and semen parameters (density, volume, count, motility, total motile count (TMC)) were compared for each group.
Results
A total of 193 subjects were studied. Median age [IQR] of the group was 18.3 [18.1-19.3], 18.6 [18.3-21.0], 18.5 [18.2-19.6] years, respectively, for Group1 (n=76), Group2 (n=21), and Group3 (n=96). TMC (million sperm) for Group1, Group2, and Group3 was: 14.6 [4.7-29.3], 4.0 [0-38.0], 34.1 [7.6-90.8], respectively. No significant difference existed between the groups for age, volume (p=0.106), or motility (p=0.197). However, density (p=0.0001), count (p=0.0001), and TMC (p=0.0002) all achieved significance; for each of these parameters, a significant difference could be shown between both Group1 vs. Group3 and Group2 vs. Group3, but not between Group1 vs. Group2.
Conclusions
Semen quality of youths with a varicocele more closely resembles that of those with bilateral UDT than those with unilateral UDT. This is very concerning and should challenge current paradigms of management for adolescents with a varicocele.
http://www.jurology.com/article/S0022-5347(13)00286-3/abstract
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