近日，来自荷兰的科学家在国际学术期刊scientific reports在线发表了他们的最新研究进展，他们发现短期急性运动并不能改善中年男性脂肪肝。

　　肝脏脂质含量上升会增加代谢性并发症的发病风险。虽然通过长期运动可以降低肝脏脂质含量，但短期急性运动是否有同样效果一直未有研究。肝脏ATP含量可能与胰岛素抵抗和肝脏脂质含量升高有关。

　　研究人员对急性运动是否能够影响肝脏脂质含量以及是否伴随着肝脏ATP含量的改变进行了实验探究。他们选取了21名男性（年龄54.8± 7.2 岁，BMI 29.7 2.2 kg/m2 ）进行了两个小时的骑行锻炼，并且一次实验是在空腹状态下进行，另一次实验是在摄取葡萄糖的情况下进行。研究人员对基线水平，运动后30分钟和运动后4小时的肝脏脂质含量进行了测量，同时也对基线水平和运动后4小时的ATP/total P比率进行了检测。结果发现与基线相比，空腹状态和补充葡萄糖状态下，运动后30分钟检测的肝脏脂质含量并没有显著差异。但是，在空腹状态下，运动后4小时肝脏脂质含量出现了升高，而这一现象受到了葡萄糖补充的阻断。

　　综上所述，该研究发现急性运动并不会降低超重的中年男性的肝脏脂肪含量，要想降低肝脏脂肪含量，改善相关代谢紊乱疾病，还是需要长期运动外加合理膳食。

　　doi:10.1038/srep09709

　　Acute exercise does not decrease liver fat in men with overweight or NAFLD

　　L. Bilet,B. Brouwers,P. A. van Ewijk,M. K. C. Hesselink,M. E. Kooi,P. Schrauwen&V. B. Schrauwen-Hinderling

　　Elevated hepatic lipid content (IntraHepatic Lipid, IHL) increases the risk of metabolic complications. Although prolonged exercise training lowers IHL, it is unknown if acute exercise has the same effect. Furthermore, hepatic ATP content may be related to insulin resistance and IHL. We aimed to investigate if acute exercise leads to changes in IHL and whether this is accompanied by changes in hepatic ATP. Twenty-one men (age 54.8 ± 7.2 years, BMI 29.7 ± 2.2 kg/m2) performed a 2 h cycling protocol, once while staying fasted and once while ingesting glucose. IHL was determined at baseline, 30 min post-exercise and 4 h post-exercise. Additionally ATP/Total P ratio was measured at baseline and 4 h post-exercise. Compared with baseline values we did not observe any statistically significant changes in IHL within 30 min post-exercise in neither the fasted nor the glucose-supplemented condition. However, IHL was elevated 4 h post-exercise compared with baseline in the fasted condition (from 8.3 ± 1.8 to 8.7 ± 1.8%, p = 0.010), an effect that was blunted by glucose supplementation (from 8.3 ± 1.9 to 8.3 ± 1.9%, p = 0.789). Acute exercise does not decrease liver fat in overweight middle-aged men. Moreover, IHL increased 4 h post-exercise in the fasted condition, an increase that was absent in the glucose-supplemented condition. These data suggest that a single bout of exercise may not be able to lower IHL.