克鲁肯贝格瘤——一种罕见病：阿曼的经验

　　KRUKENBERG TUMOURS - A RARE ENTITY: THE OMANI EXPERIENCE

　　M. Al Kalbani¹, M. Al Riyami², I. Burney³

　　Objectives: Krukenberg tumours of the ovaries are uncommon. In most cases the primary is in the gastrointestinal tract, the Stomach being the most frequent followed by the colon, breast and appendix. It carries a high mortality rate and to date no curative treatment is available. We report our experience at Sultan Qaboos University Hospital (SQUH), Oman.

　　Methods: Case notes of all Krukenberg tumours diagnosed between 2006 and 2011 were reviewed.

　　Results: Seven women were identified out of sixty patients (median age 41; range 18-60). In three, colon cancer was the primary, followed by the stomach in two, lymphoma in one and leukemia in another. Two had mucinous adenocarcinomas of the colon and stomach. Clinical presentation was variable and included backache, abdominal pain, altered bowel habits, rectal bleeding, menstrual irregularity, epistaxis and fever. CA 125 was raised in six and was not checked in one. CEA was only checked in two patients and was elevated. Ascites was present in four cases. In all but one case, the diagnosis of a metastatic Krukenberg tumour was made prior to debulking surgery. Median survival was 4 months (2-24 months). One patient is still alive 14 months after diagnosis.

　　Conclusions: The diagnosis of Krukenberg tumours requires a high index of suspicion. Out of 60 patients diagnosed to have malignant ovarian masses during the study period, 7 had Krukenberg tumours (8.5%). A national data base register for these cases is crucial.

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