[中国心脏大会]食用鱼类与心衰的相关性研究
Objective The purpose of this meta-analysis was to evaluate the association between fish consumption and incidence of heart failure (HF).Background The&nbs
Objective The purpose of this meta-analysis was to evaluate the association between fish consumption and incidence of heart failure (HF).
Background The results from observational studies suggesting the association between fish intake and HF incidence are inconsistent.
Methods A systematic search of Pubmed and Embase was performed using the keywords related to fish and HF. The pooled relative risk (RR) and corresponding 95% confidence interval (CI) were calculated using a fixed or random-effects model. The generalized least squares regression model was used to quantify the dose-response relationship between fish consumption and HF incidence.
Results Five prospective cohort studies(4750 HF events of 170231 participants)were included in our meta-analysis. Compared with those who never ate fish, individuals who consumed fish once per week had a reduced incidence of HF (RR, 0.91; 95% CI, 0.84 to 0.99). An increment of 20 g of daily fish intake was related to a 6% lower risk of HF.
Conclusions The results of our meta-analysis suggest that fish consumption is inversely associated with the incidence of HF. Fish consumption once per week or more could reduce HF incidence.
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