近日,在DDW2012上,复旦大学附属中山医院普外科主任医师,副教授,内镜中心副主任周平红就胃肠道病变的内镜微创和外科手术治疗做了精彩演讲。本研究主要评估经口内镜肌切开术治疗贲门失弛缓症的疗效和可行性。
编者按:近日,在DDW2012上,复旦大学附属中山医院普外科主任医师,副教授,内镜中心副主任周平红就胃肠道病变的内镜微创和外科手术治疗做了精彩演讲。本研究主要评估经口内镜肌切开术治疗贲门失弛缓症的疗效和可行性。
周平红教授做主题演讲
Peroral endoscopic myotomy (POEM) for esophageal achalasia: 205 cases report
Zhou, Ping-Hong; Yao, Liqing; Zhang, Yi-Qun; Cai, MingYan; Zhong, Yun-Shi; Ren, Zhong; Xu, Mei-Dong; Chen, Wei-Feng; Li, Quan-Lin; Qin, Xin-Yu
Objective: To evaluate the efficacy and the fesibility of peroral endoscopic myotomy (POEM) for esophageal achalasia (AC).
Patients and methods: The clinical data of 205 patients diagnosed as AC and received POEM were reviewed retrospectively in our center during August 2010 and October 2011. The key procedures of POEM were as following, 1) esophageal mucosal incision, 2) submucosal “tunnelling” by endoscopic submucosal dissection (ESD) technique, 3) endoscopic myotomy of the circular muscle, 4) closure of mucosal entry by hemostatic clips.
Results: The average age was 43.9 years (range 6-75), and the average duration of symptoms were 8.7 years (range 3m-50y). 202 patients received POEM successfully (98.5%). POEM procedure failed in 3 patients because of severe submucosal fibrosis due to other previous therapies. The mean operation time was 68.5 min (range 10 – 180) with a mean submucosal tunnelling length of 10.5 cm (range 8-15). The average length of endoscopic myotomy of inner circular muscle was 9.5 cm (range 7-13). No serious complicatios related to POEM were encountered. Dysphagia symptom was relieved significantly during the follow-up period in 199 patients. The mean follow-up period was 8.5 m (range 1-14).
Conclusion: As a new minimally invasive therapy for AC, POEM seems to be very effective to relieve patient’s dysphagia symptom in a short period. Further observations and long follow-up are needed to evaluate long-term outcome and complications.
(复旦大学附属中山医院普外科主任医师,副教授,内镜中心副主任 周平红)
专题链接:2012美国消化疾病周专题
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