Study: ACP offers improved outcomes compared to HA for gonarthrosis patients.
According to data from an Italian study published in the December issue of the American Journal of Sports Medicine, autologous conditioned plasma (ACP) may offer better clinical outcomes than hyaluronic acid (HA) for the treatment of gonarthrosis. The authors conducted a randomized, controlled trial of 120 patients affected by clinically and radiographically documented gonarthrosis. Overall, 60 patients received 4 intra-articular injections of ACP while 60 patients received 4 intra-articular injections of HA. Researchers found that treatment with a local injection of ACP was linked to significant improvement on Western Ontario and McMaster (WOMAC) score shortly after final infiltration, and a continuously improving sustained effect up to 24 weeks, at which point clinical outcomes were better compared with the results with HA. For patients in the HA group, the worst results were obtained for grade III gonarthrosis. Clinical results obtained in the ACP group did not show any statistically significant difference in terms of the grade of gonarthrosis.
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